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Caspase 3 antibody [HMV307] HistoMAX™

Recombinant antibody HistoMAX
Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931
Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931
Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931

Cat. No. GTX639931

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV307

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all Caspase 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Cat, Pig, Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Caspase 3. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 3,CPP32,CPP32B,SCA-1

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931

GTX639931 IHC-P Image

IHC-P analysis of human uterus cervix tissue using GTX639931 Caspase 3 antibody [HMV307] HistoMAX™.
Adenocarcinoma with strong CASP3 staining of tumor cells.

Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931

GTX639931 IHC-P Image

IHC-P analysis of human stomach antrum tissue using GTX639931 Caspase 3 antibody [HMV307] HistoMAX™.
Moderate to strong cytoplasmic caspase-3 positivity of epithelial cells of the surface epithelium.

Anti-Caspase 3 antibody [HMV307] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639931

GTX639931 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX639931 Caspase 3 antibody [HMV307] HistoMAX™.
Variable cytoplasmic caspase-3 positivity of lymphocytic cells, staining is strongest in germinal centres.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329
Currently in production