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Desmoglein 2 antibody [HL2036]

Recombinant antibody Orthogonal
Anti-Desmoglein 2 antibody [HL2036] used in Western Blot (WB). GTX637937
Anti-Desmoglein 2 antibody [HL2036] used in Western Blot (WB). GTX637937
Anti-Desmoglein 2 antibody [HL2036] used in IHC (Paraffin sections) (IHC-P). GTX637937

Cat. No. GTX637937

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2036

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all Desmoglein 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

122 kDa. ( Note )

Product Note

This antibody was raised against human Desmoglein 2 Extracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the Extracellular domain of human Desmoglein 2. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

desmoglein 2 , CDHF5 , HDGC

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Cell junction, desmosome

Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-Desmoglein 2 antibody [HL2036] used in Western Blot (WB). GTX637937

GTX637937 WB Image

Mouse tissue extract (50 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Desmoglein 2 antibody [HL2036] (GTX637937) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Desmoglein 2 antibody [HL2036] used in Western Blot (WB). GTX637937

GTX637937 WB Image

Orthogonal

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Desmoglein 2 antibody [HL2036] (GTX637937) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

Anti-Desmoglein 2 antibody [HL2036] used in IHC (Paraffin sections) (IHC-P). GTX637937

GTX637937 IHC-P Image

Desmoglein 2 antibody [HL2036] detects Desmoglein 2 protein by immunohistochemical analysis.
Sample: Paraffin-embedded mouse tissue.
Desmoglein 2 stained by Desmoglein 2 antibody [HL2036] (GTX637937) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations